Abstracts (first author)

Talk 

Evolutionary “tinkering” in the origin of the insect terminal patterning system

Author(s): Chipman AD, Weisbrod A

Summary:

A key early process in development is the determination of the embryonic axes. The anterior-posterior axis in insects is determined by a series of signaling pathways and transcription factors. These are best known from the fruitfly Drosophila melanogaster, where the torso pathway activates a number of posterior transcription factors, while interacting diffusible factors define the anterior. We have cloned the homologues of most of the key players in terminal patterning from the milkweed bug Oncopeltus fasciatus, focusing on huckebein, torsolike, hunchback, orthodenticle and tailless. We then studied their expression and function, and their interaction with other early developmental pathways. Our results show that many of the pathways known to be involved in Drosophila terminal patterning have different roles in Oncopeltus development. We suggest that their roles in Drosophila are derived from the more ancestral roles still preserved in Oncopeltus. We use our results to discuss a model for the evolution of the terminal patterning system in insects, and show that the evolution of this pathway is a classic example of evolutionary "tinkering", where different elements are co-opted independently into a single novel patterning system.


Video


Contacts

Chairman: Octávio S. Paulo
Tel: 00 351 217500614 direct
Tel: 00 351 217500000 ext22359
Fax: 00 351 217500028
email: mail@eseb2013.com

Address

XIV Congress of the European Society for Evolutionary Biology

Organization Team
Department of Animal Biology (DBA)
Faculty of Sciences of the University of Lisbon
P-1749-016 Lisbon
Portugal

Website

Computational Biology & Population Genomics Group 
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