Abstracts (first author)

Poster 

Cell sacrifice in the gut: an adaptive response towards Nosema spp. infection in honey bees

Author(s): Kurze C, Huang Q, Moritz RFA

Summary:

The microsporidian Nosema ceranae is a natural parasite of the Asian honeybee Apis cerana but is now also a widespread cause of Nosemosis in the European honey bee A. mellifera. N. cerana infections can have severe effects on honey bee fitness at the individual and colony level. We found that the extensive breeding effort by Danish beekeepers against the native microsporidian parasite N. apis has produced a Nosema tolerant honey bee strain, which revealed a strongly up-regulated immune response when challenged by N. cerana infection compared to an unselected strain. After transmission via the fecal-oral route, spores normally germinate in the midgut, where they penetrate, replicate and destroy the cells of the gut epithelium. To understand the effect of the altered immune response on the level of infestation and destruction of the midgut epithelium, we compare sections between the selected and an unselected strain over the course of infection. We discuss these results in the context of an adaptive immune response and other underlying biological mechanisms of the selected strain against N. ceranae infection.



Contacts

Chairman: Octávio S. Paulo
Tel: 00 351 217500614 direct
Tel: 00 351 217500000 ext22359
Fax: 00 351 217500028
email: mail@eseb2013.com

Address

XIV Congress of the European Society for Evolutionary Biology

Organization Team
Department of Animal Biology (DBA)
Faculty of Sciences of the University of Lisbon
P-1749-016 Lisbon
Portugal

Website

Computational Biology & Population Genomics Group 
Close