Abstracts (first author)

Poster 

Tropical African cattle a unique model for the study of livestock adaptation

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Author(s): Bahbahani HM, Hanotte OH

Summary:

Indigenous cattle populations of Africa have a unique history which makes them particularly suitable for the understanding, at the genome level, of environmental adaptation. African taurine cattle Bos taurus taurus were the first to arrive on the continent. They were followed by the humped Bos taurus indicus zebu from their centre of domestication on the Indian subcontinent. The result of these migrations is a mosaic of zebu-taurine cattle population adapted to a diversity of local environments (e.g. semi-dry desert, humid and sub-humid forested areas) and production systems (e.g. pastoral, small-holder). Here, we use genomic tools to unravel genetic positive signature of selection in the East African shorthorn zebu, a locally indigenous adapted cattle from Western Kenya. We show that its autosomal genome structure is a complex make-up of taurine and zebu background while its mitochondrial DNA genome is of taurine origin only. Positive signatures of selection are detected through high density SNP chip genotyping and full genome sequencing. They include genes which may be associated with adaptation to disease challenge or reproductive function. An example of these genes is RXFP2, which is involved in testicular descent development, and horn development. Analysis of the mitochondrial DNA reveal signature of purifying selection against deleterious mutations.



Contacts

Chairman: Octávio S. Paulo
Tel: 00 351 217500614 direct
Tel: 00 351 217500000 ext22359
Fax: 00 351 217500028
email: mail@eseb2013.com

Address

XIV Congress of the European Society for Evolutionary Biology

Organization Team
Department of Animal Biology (DBA)
Faculty of Sciences of the University of Lisbon
P-1749-016 Lisbon
Portugal

Website

Computational Biology & Population Genomics Group 
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